At Profil, our commitment to advancing metabolic health research is driven by our use of state-of-the-art technologies, such as Indirect Calorimetry. This highly accurate method is pivotal for understanding not only resting energy expenditure (REE) and diet-induced thermogenesis (DIT) but also for measuring substrate oxidation rates. By assessing the respiratory exchange ratio (RER) or respiratory quotient (RQ), we can determine the preferred substrates—fat, carbohydrates, or protein—used for energy by the body, which are key components in managing and researching metabolic diseases.
What is Indirect Calorimetry?
Indirect Calorimetry measures oxygen consumption and carbon dioxide production to assess energy expenditure. This non-invasive technique accurately determines how different diets and treatments impact metabolic rates. At Profil, we ensure the accuracy of our data by conducting measurements under strictly standardized conditions: subjects are at rest, have fasted overnight, and have not consumed a protein-rich meal the evening before to ensure consistency in test results.
Why Use Indirect Calorimetry?
- Assessment of Metabolic Components: By measuring REE and DIT, we can evaluate how much energy the body expends and which macronutrients are preferred under different dietary conditions or therapeutic interventions.
- Precision and Reproducibility: Indirect Calorimetry provides exact measurements crucial for understanding individual metabolic rates and the effects of therapeutic interventions.
- Customized Treatment Plans: These insights allow for tailored nutritional advice and treatment plans, improving patient outcomes in clinical trials.
Advantages at Profil:
- Accurate Metabolic Rate Measurement: Enables precise quantification of REE and DIT.
- Integration into Clinical Trials: Quick and seamless integration into any trial design thanks to its non-invasive nature and the rapid availability of results.
- Safe for Patients: As a non-radiative method, it’s a safer alternative to other assessment methods, offering comfort and convenience to participants.
Challenges We Overcome
Maintaining high standards of test condition standardization is critical to our success, ensuring that every participant preparation and measurement adheres strictly to our protocols for reliable and consistent results.
Join Us
Discover more about how Profil uses cutting-edge technology like Indirect Calorimetry to enhance our understanding of metabolic health and improve patient care. Visit our website or contact us for more information on how we incorporate these technologies into our research.