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Diabetes treatment
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Alternative route insulins
Insulin analogues
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Bodpod / body composition
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Adipose tissue and muscle biopsy
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Trial stages
First drug approved for NASH
BfArM speeds up the approval process for clinical trials in Germany
Correct interpretation of key CGM metrics
GLP-1 based drugs: Could Elon Musk’s weight loss weapon help us, too?
Profil's scientific publications in 2023 - an overview
A novel long-acting Amylin analogue for the management of obesity
Free Live Online Seminar: IMP management services for multi and single-center clinical trials in EU
CTR 536/2014: First approvals and our experience with CTIS (Part 3)
Profil World - The clinical diabetes research newsletter - Jun 2023
Corporate Social Responsibility in Clinical Trials
Unique Device Identifier, UDI, examplified by Profil’s class IIb medical device “ClampArt” (Part II)
Profil World - The clinical diabetes research newsletter - Mar 2023
Unique Device Identifier, UDI, examplified by Profil’s class IIb medical device “ClampArt” (Part I)
IDF School of Diabetes: Biosimilar Insulins - Complimentary online course
CTR 536/2014: CTIS - the single entry point for submitting clinical trials in the EU (Part 2)
CTR 536/2014: Where do we come from and where do we go? (Part I)
Profil World - The clinical diabetes research newsletter - Dec 2022
Recent Profil Publications on Biosimilar Insulins
Free Live Online Seminar: Profil - the leading CRO for metabolic research
Insulin Infusion System Failure – What’s the matter with the infusion sets?
SURMOUNT-1 demonstrates substantial weight loss with Tirzepatide
Profil World - The clinical diabetes research newsletter - Sep 2022
What role does COVID-19 play in the pathogenesis of diabetes mellitus
Free Live Online Seminar: Ethnic Bridging in Drug Development
The Profil Science Report 2021 - "What Science Can Do"
Don't let clinical trial subject recruitment hold you back!
Pharmacological options for weight management and people with T2D
Free Online Seminar: Artificial Intelligence - what is the hype about?
New glucose clamp quality parameter: absolute control deviation
The German Digital Healthcare Act and DiGA: what is in it for diabetes? (Part III)
The German Digital Healthcare Act and DiGA: what is in it for diabetes? (Part II)
The German Digital Healthcare Act and DiGA: what is in it for diabetes? (Part I)
Free Online Seminar: Standardised nutrition in early phase clinical research
A new era in type 1 diabetes treatment – AID systems and what else?
A pathophysiological update of the incretins
GLP-1 agonists: an option for NAFLD?
Profil World - The clinical diabetes research newsletter - October 2021
Free Online Seminar: Advancements in oral insulin development
Oral insulin: The future of insulin therapy?
EU Clinical Trials Regulation (EU-CTR) enters application on 31 January 2022
Profil World - The clinical diabetes research newsletter - July 2021
Can Remote Decentralised Clinical Trials enhance clinical research?
Gender ratio in clinical trials – are there less female trial participants?
Reporting of study results: a challenge?
Profil World - The clinical diabetes research newsletter - March 2021
Profil leads the way in establishing audit trail review procedures in clinical studies using visual data analytics
Free Online Seminar: Audit trail review in clinical studies using visual data analytics
Can serious games motivate teenagers with diabetes to adhere to their treatment?
Running clinical trials at Profil during pandemic times
β3-adrenoceptor agonist Mirabegron – a candidate anti-obesity drug?
Once-weekly basal insulin analogue in clinical development
Glycemic control in type 1 diabetes – effects of diabetes technology and socioeconomic status
Profil World - The clinical diabetes research newsletter - October 2020
Free Online Seminar: Profil - the leading CRO for metabolic research
Profil starts in-house production of tubing sets for ClampArt®, reinforcing the quality of world-class glucose clamp trials
The rollercoaster life of inhaled insulin
Heart failure: SGLT2 inhibitors moving beyond diabetes
Bringing the real world to clinical research: the use of wearables in pivotal trials
When Artificial Intelligence and Artificial Pancreas meet
Non invasive CGM; hope at the horizon?
Free Online Seminar on insulin biosimilars
Think Tank highlights CROs role the adoption of AI-powered health innovation
Fighting Corona: Profil's contribution
Clinical study shows better clamp quality with Clamp-PID algorithm
A novel method to determine the pharmacodynamic onset of action of prandial insulins
Profil World - The clinical diabetes research newsletter - February 2020
Type 1 Diabetes and mild cognitive impairment
Free Online Seminar on early phase obesity research
Trustworthy AI in healthcare - it's TIME TO DELIVER
Beer or wine or both – and if both, in which order?
Profil World - The clinical diabetes research newsletter - November 2019
Lipohypertrophy – New insights into an old issue?
What news in the treatment of Type 2 diabetes was presented at EASD 2019?
Finally breakthrough in the immunological approach to type 1 diabetes
Current developments in approaches to bridging studies
iPDM Goes Europe: tangible impact on diabetes patients and care
New PID-algorithm for automated glucose clamps
"Profil World" - The clinical diabetes research newsletter - July 2019
Dual-hormone artificial pancreas systems
Dr. Tim Heise about Profil's 2018 Science Report
Is there a ‘true’ insulin time action profile?
Applications of iontophoresis in studies investigating microvasculature
The ideal basal insulin?
"Profil World" - The clinical diabetes research newsletter - May 2019
Profil is co-founder of KomIT
NAFLD/NASH: a ticking bomb not yet defused
Profil joined iPDM-GO
Free Online Seminar on Diagnosis of NAFLD
Are soccer players with dark skin tone more likely to receive red cards?
"Profil World" - The clinical diabetes research newsletter - February 2019
Artificial pancreas in type 2 diabetes
Free Online Seminar titled "Understanding the results of glucose clamp studies"
Digital Diabetes: better trials, better drugs, better care
Glucose-Infusion-Rate based categorization of glucose clamps
Update on Brexit: Impact on future and current clinical trials in Germany
Pramlintide as adjunct therapy for the treatment of type 1 diabetes
New data on cardiovascular outcomes with SGLT2 inhibitors
Glucose-Responsive Insulin
New strategies for the treatment of obesity and metabolic dysfunctions
Profil at 18th Annual Diabetes Technology Meeting
Artificial Intelligence to Screen for Diabetic Retinopathy; The Times They Are A-Changin‘.
New timelines for the EU Portal and implementation of the EU Clinical Trial Regulation
"Profil World" - The clinical diabetes research newsletter - October 2018
54th EASD Annual Meeting – Profil’s contributions to the scientific sessions
Profil explores opportunities for artificial pancreas in type 2 diabetes
Work stress is the new smoking
Profil at EASD Annual Meeting 2018
Do-It-Yourself Artificial Pancreas systems (DIY APS)
Targeting the incretin/glucagon system: a glimmer of hope
Even moderate overweight increases the risk for cardiovascular disease, recent study says
The new European Medical Device Regulation (MDR)
Clamp studies with ultra-long-acting insulins – New challenges for an old procedure
"Profil World" - The clinical diabetes research newsletter - July 2018
Diabetes: A paradigm case for rewarding innovation in value-based healthcare
Gut Microbiota and Type 2 Diabetes
CGM in pregnant women with type 1 diabetes
Cardiovascular endpoints in trials with glucose-lowering medications
Smart ideas for noninvasive glucose monitoring
SUSTAIN 7 - Semaglutide is superior to Dulaglutide
Vitamin D supplementation – is there a role in type 1 diabetes?
Profil announces new live Online Seminar Session
Influence of Technical Downtime on the Outcome of Automated Glucose clamps
D4kids: Profil joined a new pan-European Artificial Pancreas initiative
Profil is committed to the highest quality - including the training of our staff
Cardiovascular outcome trials of incretin drugs: what have we learned?
Nutrition standardization during clinical trials: Methods of standardized food intake
Insulin injection: recent improvements and alternatives
"Profil World" - The clinical diabetes research newsletter - March 2018
Flow-Mediated Vasodilation: why we do it and how to do it
Pancreatic ß-cell function changes in response to pharmacological or life-style interventions
Free Online Seminar on endothelial function in clinical trials using Flow-Mediated Vasodilation
Implementation of EU directive 536/2014: Ethic committees prepare for the next level
Dr. Tim Heise about Profil's 2017 Science Report
Advanced precision of Continuous Whole Blood Glucose concentration measurements
Artificial pancreas for type 2 diabetes: the CLOSE project
Bringing glucose clamps up to speed for novel insulins
Health claims & the need for scientific evidence in food studies
The need for speed
"Profil World" - The clinical diabetes research newsletter - November 2017
Treatment with SGLT2 inhibitors: is there hope for renal protection?
Can a dual-hormone closed loop delivery systems become a “technical cure” of diabetes?
Biomarkers for vascular integrity in patients with diabetes mellitus (Part 2)
Insulin therapy: Profil presented at EASD 2017
Novelties in the treatment of Type 2 diabetes presented at the EASD 2017
Minimal Blood Loss with Automated Glucose Clamps: A new configuration of ClampArt
Non-invasive liver fat and liver stiffness screening at Profil
Alternate –Day Fasting: Any better than other Diets?
Inhaled insulins - a valid option in the treatment of diabetes?
HbA1c, a diabetes marker for the past and for the future?
Free Online Seminar on digitalization in diabetes by Prof. Lutz Heinemann
One insulin tablet a day… Profil study shows promise for alternative to insulin injections
Biomarkers for vascular integrity in patients with diabetes mellitus
Glucose Clamps: 2 steps towards hepatic and peripheral insulin sensitivity
"Profil World" - The clinical diabetes research newsletter - July 2017
Error Grid Analysis
Update to the EU Directive 536/2014 and Brexit
Looking beyond blood glucose - the islet of Langerhans
Considering the Complexity of Food-Drug Interactions for drug development
Smart Insulin Patches or Glucose-Responsive Insulin Delivery Systems
A different design of Glucose Clamps: Fixed Rate of Blood Glucose Change rather than Fixed Blood Glucose Levels
Targeting LDL cholesterol – How low do we need to get it? And at what price…?
Don't miss ADA 2017 President's Oral Session
Will noninvasive glucose monitoring end in tears?
First in Human (FIH) Trials: New draft guideline for Risk Mitigation
New Study about Sugar vs. Calorie-free Sweeteners
"Profil World" - The clinical diabetes research newsletter - April 2017
Profil recent publications on diabetes
How clinical trial results are distorted by reporting bias
Your blood glucose meter might not be sufficiently accurate! (Update 03/2017)
How do SGLT2 inhibitors improve cardiovascular outcomes?
Patient initiated research – How involvement of patients could help improve diabetes research
Glucose clamps: 2 steps towards insulin sensitivity adjusted for glucose effectiveness
The New Clinical Trials Regulation EU No 536/2014 - Amendments to the German Drug Law
New Biosimilar Insulin Study Published
Oral insulins still under development
Profil Online Seminar Series on Diabetes and Obesity
Improved Algorithm for Automated Glucose Clamps
Dr. Tim Heise about Profil's 2016 Science Report
Liver first ? Part III: Medical Needs
Liver first ? Part II: NASH and NAFLD
Modifying insulin kinetics - requirements and limitations (Part 2)
Glucagon - the rising star in diabetes research (Part 2)
"Profil World" - Novel clamp method, upcoming online seminar with JJ Meier, history of Glucagon research
Profil scientists publish new clamp method to evaluate glucose measurement performance
Glucagon - the rising star in diabetes research (Part 1)
TECOS study: No CVD risk or heart failure with sitagliptin in high-risk diabetes patients
Medications for type 2 diabetes: a short historical perspective
Federal State Minister visited Profil
100% would recommend running a clinical trial at Profil
Modifying insulin kinetics - clinical requirements and limitations (Part 1)
Clinical Data Management - would you like to become a specialist or an all-rounder?
"Profil World" - The clinical diabetes research newsletter's July edition
Liver first? The liver in diabetes and cardiovascular disease (Part I)
New review of hyperinsulinemic euglycemic glucose clamp technique
Addressing postprandial glucose excursion – What is the evidence?
Walking the GIR-smoothing tightrope – data refinement versus data impairment
Profil congratulates Senseonics on CE Mark for 90-day implantable CGM sensor
The New Clinical Trials Regulation EU No 536/2014 - Update (02/2017)
What does a CRA do at Profil?
Ever considered becoming a research physician at a CRO?
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